List of Treatments for Pulmonary Hypertension

Adcirca (Tadalafil)

Overview
Adcirca is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise in cases of pulmonary arterial hypertension. Adcirca may be referred to by its drug name, tadalafil.… read more

Adempas (Riociguat)

Overview
Adempas is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise and function in adult cases of chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary… read more

Aldactone (Spironolactone)

Overview
Aldactone is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat hypertension, heart failure, edema, and other conditions. In cases of pulmonary hypertension, Aldactone may be… read more

Alyq (Tadalafil)

Overview
Alyq is approved by the U.S. Food and Drug Administration (FDA) for the treatment of pulmonary arterial hypertension (PAH) to improve exercise ability. People eligible for this treatment typically have New York…

Atrial septostomy

Overview
Some people with advanced pulmonary arterial hypertension (PAH) and severe right heart failure may be candidates for atrial septostomy surgery. Atrial septostomy can relieve pressure in the right side of the… read more

Bumex (Bumetanide)

Overview
Bumex is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat edema associated with congestive heart failure and other conditions. In cases of pulmonary hypertension, Bumex may… read more

Cardizem (Diltiazem)

Overview
Cardizem is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat hypertension, chronic stable angina, and angina due to coronary artery spasm. Cardizem is sometimes prescribed to… read more

Clinical trials

Overview
Depending on several factors, you may be eligible to participate in clinical trials studying new treatments for pulmonary hypertension. Eligibility may be based on specifics of your condition, such as which… read more

Coumadin (Warfarin)

Overview
Coumadin is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat and prevent thromboembolic events. Coumadin may also be prescribed in cases of pulmonary hypertension, especially… read more

Digoxin

Overview
Digoxin is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat adults with mild to moderate heart failure and atrial fibrillation. It is also approved to treat children with… read more

Exercise

Overview
Years ago, doctors used to believe that people with pulmonary hypertension (PH) should avoid exercise as dangerous to their health. More recently, most PH specialists have come to believe that regular sessions… read more

Flolan (Epoprostenol)

Overview
Flolan is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise capacity in cases of pulmonary arterial hypertension (PAH). Flolan may be referred to by its drug name,… read more

Heart-lung transplant

Overview
Heart-lung transplant may be an option for some people with end-stage heart and lung disease due to pulmonary hypertension (PH). However, heart-lung transplant also poses significant risk for serious… read more

Lanoxin (Digoxin)

Overview
Lanoxin is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat mild to moderate heart failure and atrial fibrillation in adults. Lanoxin may also be prescribed in cases of… read more

Lasix (Furosemide)

The Lasix brand name has been discontinued in the U.S. Generic alternatives may be available.

Overview

Lasix is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat hypertension and edema…

Letairis (Ambrisentan)

Overview
Letairis is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise capacity and limit disease progression in cases of pulmonary arterial hypertension (PAH). Letairis is… read more

Liqrev (Sildenafil)

Overview
Liqrev is approved by the U.S. Food and Drug Administration (FDA) for the treatment of pulmonary arterial hypertension (PAH). Liqrev is prescribed to improve exercise ability and delay clinical worsening in…

Lung transplant

Overview
Lung transplant can prolong survival and improve lung function and quality of life in some people with pulmonary hypertension (PH). However, lung transplant also poses significant risk for serious… read more

Metolazone

Overview
Metolazone is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat hypertension and edema associated with congestive heart failure. In cases of pulmonary hypertension, Metolazone… read more

Mitral valve surgery

Overview
In some people with pulmonary hypertension (PH), the disease is caused by damage or a defect of the mitral valve of the heart. Mitral valve surgery can potentially be an effective treatment for PH in certain… read more

Nutrition

Overview
Like everyone else, people with pulmonary hypertension (PH) feel their best when they consistently eat a healthy, balanced diet. By choosing the right foods, people with PH can improve disease symptoms and… read more

Opsumit (Macitentan)

Overview
Opsumit is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to delay disease progression in cases of pulmonary arterial hypertension (PAH). Opsumit may be referred to by its drug… read more

Opsynvi (Macitentan and Tadalafil)

Overview
Opsynvi, approved by the U.S. Food and Drug Administration (FDA), is indicated for the chronic treatment of adults with pulmonary arterial hypertension (PAH, WHO group 1) at WHO functional class 2 and 3…

Orenitram (Treprostinil)

Overview
Orenitram is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise capacity in cases of pulmonary arterial hypertension (PAH). Orenitram may be referred to by its drug… read more

Oxygen therapy

Overview
People with pulmonary hypertension caused by conditions such as chronic obstructive pulmonary disease (COPD), interstitial lung disease, and sleep apnea may develop hypoxia, or low levels of oxygen in the… read more

Procardia (Nifedipine)

The Procardia brand name has been discontinued in the U.S. Generic alternatives may be available.

Overview

Procardia is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to manage vasospastic…

Procardia XL (Nifedipine)

Overview
Procardia XL is approved by the U.S. Food and Drug Administration (FDA) for the treatment of vasospastic angina (chest pain due to spasms in the coronary arteries), chronic stable angina, and hypertension (high…

Pulmonary rehabilitation

Overview
People with pulmonary hypertension (PH) may develop shortness of breath that makes it difficult to walk and perform other daily activities. Pulmonary rehabilitation is a program designed to improve your ability… read more

Pulmonary thromboendarterectomy (PTE)

Overview
Pulmonary thromboendarterectomy (PTE) surgery is a potential cure for some people with chronic thromboembolic pulmonary hypertension (CTEPH). CTEPH is a type of pulmonary hypertension wherein blood clots in… read more

Remodulin (Treprostinil)

Overview
Remodulin is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise capacity in cases of pulmonary arterial hypertension (PAH). Remodulin is sometimes prescribed when… read more

Revatio (Sildenafil)

Overview
Revatio is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise and delay disease progression in cases of pulmonary arterial hypertension. Revatio may be referred to… read more

Tracleer (Bosentan)

Overview
Tracleer is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise capacity and limit disease progression in adults with pulmonary arterial hypertension (PAH). Tracleer… read more

Tyvaso (Treprostinil)

Overview
Tyvaso is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise capacity in cases of pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with… read more

Uptravi (Selexipag)

Overview
Uptravi is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to delay disease progression and reduce the risk of hospitalization in cases of pulmonary arterial hypertension (PAH).… read more

Veletri (Epoprostenol)

Overview
Veletri is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve exercise capacity in cases of pulmonary arterial hypertension (PAH). Veletri may be referred to by its drug… read more

Ventavis (Iloprost)

Overview
Ventavis is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to improve symptoms and exercise capacity and to avoid deterioration in cases of pulmonary arterial hypertension (PAH).… read more

Winrevair (Sotatercept-csrk)

Overview
Winrevair is approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with pulmonary arterial hypertension (PAH, World Health Organization group 1). It is used to help increase exercise…