PHOSPHODIESTERASE 5 (PDE5) INHIBITOR
Overview
Liqrev is approved by the U.S. Food and Drug Administration (FDA) for the treatment of pulmonary arterial hypertension (PAH). Liqrev is prescribed to improve exercise ability and delay clinical worsening in people with PAH. Liqrev is also known by its drug name, sildenafil.
Sildenafil belongs to the phosphodiesterase 5 (PDE5) inhibitor category. It works by relaxing blood vessels in the lungs, which helps to decrease blood pressure and improve blood flow, reducing the workload on the heart and improving exercise capacity.
How do I take it?
Prescribing information states that Liqrev is taken orally as a suspension, three times per day. It is important to take Liqrev exactly as prescribed by a health care provider.
Side effects
Common side effects of Liqrev include headache, dyspepsia (indigestion), flushing (redness and warmth of the skin), pain in the limbs, myalgia (muscle pain), back pain, and diarrhea.
Rare but serious side effects may include sudden decrease or loss of vision or hearing. Serious vaso-occlusive crises may occur in people with pulmonary hypertension secondary to sickle cell disease. The drug is not recommended for people with pulmonary veno-occlusive disease (PVOD) due to the risk of pulmonary edema (fluid buildup in the lungs).
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Label: Liqrev — Sildenafil Suspension — DailyMed