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Can A PH Patient Be In More Than One WHO Designated Group At The Same Time?

A myPHteam Member asked a question 💭
Scottsdale, AZ
May 3, 2024
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A myPHteam Member

Heather this is the AI answer I got. The one thing I would say is that PAH is a beast all its own as it originates on the right side of the heart and is considered post-capillary. All the other classifications originate on the left side of the heart and are considered pre-capillary. I hope that makes sense.

Yes, a patient with pulmonary hypertension (PH) can potentially fall into more than one World Health Organization (WHO) category. Let me explain further:

1. **WHO Classification of PH**:
- The WHO classifies patients with PH into five groups based on etiology¹:
- **Group 1**: Pulmonary arterial hypertension (PAH), also known as precapillary PH.
- **Group 2**: PH due to left-sided heart disease.
- **Group 3**: PH due to lung disorders and hypoxemia.
- **Group 4**: PH due to pulmonary artery obstructions.
- **Group 5**: PH associated with different or mixed mechanisms.

2. **Overlap Syndromes**:
- Some patients may exhibit features of more than one category, leading to overlap syndromes.
- For example, a patient with chronic lung disease (such as chronic obstructive pulmonary disease or interstitial lung disease) may also have obstructive sleep apnea, resulting in both group 3 and group 5 PH.
- These cases can be challenging to classify definitively, and individual patient management may require a nuanced approach.

3. **Intermediate Risk Categories**:
- Additionally, PAH specialists often split the intermediate-risk category into two subcategories to guide treatment decisions².
- These subcategories help tailor treatment plans for patients based on their specific risk profiles.

In summary, while patients are primarily classified into one WHO group, there can be overlap or complexity in certain cases. Accurate diagnosis and personalized management are crucial for optimizing patient outcomes. Always consult with a healthcare professional for individualized advice and treatment options. 😊🌟¹²

If you have any more questions or need further clarification, feel free to ask!

Source: Conversation with Bing, 5/4/2024
(1) Pulmonary hypertension due to lung disease and/or hypoxemia ... - UpToDate. https://www.uptodate.com/contents/pulmonary-hyp....
(2) PAH Life Expectancy & Risk Status | WHO Functional Class. https://www.pahinitiative.com/pah-life-expectancy.
(3) Types of Pulmonary Hypertension: The WHO Groups. https://phassociation.org/types-pulmonary-hyper....
(4) PH in Patients With End-Stage HF: Diagnostic and Therapeutic Approaches. https://www.acc.org/latest-in-cardiology/articl....

UpToDate
PH in Patients With End-Stage HF: Diagnostic and Therapeutic Approaches - American College of Cardiology
PH in Patients With End-Stage HF: Diagnostic and Therapeutic Approaches - American College of Cardiology
Types of Pulmonary Hypertension: The WHO Groups
Types of Pulmonary Hypertension: The WHO Groups
PAH Life Expectancy & Risk Status | WHO Functional Class
PAH Life Expectancy & Risk Status | WHO Functional Class
May 4, 2024
A myPHteam Member

Heather, I know how exhausting it can be complicated medical needs and a whole slew of doctors. Sending good juju your way!

May 5, 2024
A myPHteam Member

(I have other possibly contributing factors including the previous Cancer surgery removing part of my right lung and 1/3 of my pericardium, chemo toxicity damage to my lungs, etc)

May 4, 2024
A myPHteam Member

Thank you soooo much. Yes, apparently I fall into that "overlap" syndrome with Groups 1 and 2. That really helps and I am going to actually print that out to have in front of me. I now have FOUR doctors having a group discussion next week to fine tune my care...It is both unnerving and reassuring at the same time.

May 4, 2024
A myPHteam Member

WHO needs to experience the devastating condition of not bring able to move period without gasping.
WHO? They are liable for many life altering lung conditions by their abject and political and indifference stance on the ravages of covid/long covid/all covid (subliminal) ingredients vaccines!!! So sorry good people here at this group of patients simply hoping and praying for correct medical care to pushback against PAH!

May 4, 2024

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